This educational activity is supported through the AAFP's in-cooperation-with agreement with the Collaborative for REMS Education (CO*RE), that received an independent educational grant from the ER/LA Opioid Analgesic REMS Program Companies (RPC). Please see www.er-la-opioidREMS.com for a list of the member companies. This activity is designed to be fully-compliant with the ER/LA Opioid Analgesic REMS education requirements issued by the U.S. Food and Drug Administration.