Disclosure Statements: It is the policy of the AAFP that all CME planning committee/faculty/authors/editors/staff disclose relationships with commercial entities upon nomination/invitation of participation. Disclosure documents are reviewed for potential conflicts of interest and, if identified, they are resolved prior to confirmation of participation. Only those participants who have no conflict of interest or who agree to an identified resolution process prior to their participation were involved in this CME activity.

Disclosures: Dr. Weiss, Dr. Melton, Ms. Gangel, Ms. Harden, and Mr. Carlson have returned disclosure forms indicating they have no financial interest in or affiliation with any commercial provider or providers of any commercial services discussed in this material.

This educational activity is supported through the AAFP’s in-cooperation-with agreement with the Collaborative for REMS Education (CO*RE), that received an independent educational grant from the ER/LA Opioid Analgesic REMS Program Companies (RPC). Please see www.er-la-opioidREMS.com(www.er-la-opioidREMS.com) for a list of the member companies.

This activity is designed to be fully compliant with the ER/LA Opioid Analgesic REMS education requirements issued by the U.S. Food and Drug Administration.